A mAb2 is a full-length antibody with an Fcab in place of the normal Fc region. With these additional binding sites, mAb2 bispecific monoclonal antibodies can bind two different targets at the same time.
mAb2 bispecific monoclonal antibodies maintain the full functionality, structural integrity, and stability of ordinary antibodies.
mAb2 - Genuine bispecific monoclonal antibodies
A mAb2 (pronounced “mAb-square”) is a full-length antibody in which the normal Fc region has been replaced by an Fcab. Thus, mAb2 bispecific monoclonal antibodies can bind two different antigens at the same time. In excess of 20 mAb2 have been successfully generated over the last 12 months.
F-star’s mAb2 bispecific antibody products:
- Look like monoclonal antibodies; comparable structure
- Work like monoclonal antibodies; retain all antibody functionality
- Behave like monoclonal antibodies; maintain manufacturing characteristics
- Perform beyond monoclonal antibodies; offering therapeutic synergy through bispecificity
Our Modular Antibody Technology platform creates virtually limitless product opportunities; and is unprecedented in the ease of development and manufacturing genuine bispecific antibody products.